EVALUASI SIFAT FISIK TABLET FLOATING FUROSEMIDE DENGAN MATRIKS CARBOPOL
نویسندگان
چکیده
Furosemide is a sulfonamide-derived diuretic drug which an alternative treatment for heart failure. was made into slow-release tablets to improve the criteria poor furosemide and maximize its absorption in stomach. The purpose of this study determine whether floating with concentration 23% carbopol matrix could meet requirements evaluating physical properties compared theoretically literatur. research design used pre-experimental. In study, results weight uniformity test showed that there were no deviations from column A B, tablet hardness average 5.4 kg, friability % value 0.08%, lag time 184 seconds, duration 8 hours. From data, it can be concluded fulfills all evaluations
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ژورنال
عنوان ژورنال: Jurnal ilmiah farmasi Akademi Farmasi Jember
سال: 2023
ISSN: ['2615-756X', '2503-4707']
DOI: https://doi.org/10.53864/jifakfar.v6i1.132